- Provides a quick, body-friendly burst of brain-enhancing energy without the jittery caffeine vibe
- Works at the cellular level, supporting mitochondrial health and efficiency to help the power plants in your cells create energy
- Promotes heart & nerve cell function
- 1 package of Unfair Advantage contains 30 mini-shots (30 servings)
- New proprietary liposomal delivery system uses Brain Octane® oil and other special fats to help your body preferentially absorb Active PQQ™ and CoQ10 to power peak performance
What would you consider an unfair advantage? How about a quick, body-friendly burst of brain-enhancing energy? Call on Unfair Advantage anytime you need a boost without that jittery caffeine vibe.
Unfair Advantage works on the cellular level. It supplies your mitochondria with the raw materials they need to repair themselves and power your body at full-blast. The result is amazing: clean, focused energy that can only be described as feeling on your game. It’s just you being awesome.
INGREDIENTS & USE
Unfair Advantage pairs Active PQQ (a unique composition of Pyrroloquinoline quinone) with CoQ10 in a synergistic energy formula. Unfair Advantage uses a proprietary liposomal delivery system designed for maximum bioavailability using Brain Octane® oil and a blend of other special fats so your body will preferentially absorb them, which means a noticeable effect so you can perform your best.
Ingredients: Ingredients: Purified water, glycerin, caprylic acid triglycerides from highly refined coconut oil (Bulletproof Brain Octane oil), natural flavors, phosphatidylcholine, palmitic acid, oleic acid, ubiquinone, pyrroloquinoline quinone, gum arabic, xanthan gum. All ingredients are non-GMO, product contains no fillers, dyes or other junk.
If you are 18 years or younger, pregnant or lactating, on medication (including blood pressure medication), have a medical condition, or are allergic to any listed ingredients, please consult your health care practitioner before using this product. Do not use if safety seal is broken or missing.
Refer to expiration date on your package
Unfair Advantage - CoQ10 & PQQ
SCIENCE & RESEARCH
Active PQQ™ is a special form of PQQ that's encased in a lipid blend including Brain Octane oil to support enhanced absorption. Common PQQ supplements available at your local health food store are in the disodium salt form of PQQ, which is well studied in animals with positive effects, but the effects are dramatically reduced for humans because this particular form precipitates out in an acidic environment like your stomach. This means you don't absorb it effectively, and don't feel the effects you should.
The Active PQQ™ is then paired with CoQ10, a well known enhancer of mitochondrial function to increase the overall effects. Both CoQ10 and PQQ occur naturally in the body, and are integral to good mitochondrial function and cellular energy production.
There is nothing quite like the feeling you get when your mitochondria turn on. This is the cellular energy that affects your brain first, where you have a very dense amount of mitochondria.
Unfair Advantage™ also increases mitochondria biogenesis, your body's ability to create new, more effective mitochondria. This means that your body will understand that it will benefit from having better power plants in your cells, and will clear out old mitochondria and replace it with new mitochondria. It also boosts energy production and function of existing mitochondria.
Pyrroloquinoline quinone increases the expression and activity of Sirt1 and -3 genes in HepG2 cells.
Zhang J, Meruvu S, Bedi YS, Chau J, Arguelles A, Rucker R, Choudhury M.
Nutr Res. 2015 Sep;35(9):844-9. doi: 10.1016/j.nutres.2015.06.014. Epub 2015 Jul 2.
PMID: 26275361 [PubMed - in process]
Pyrroloquinoline quinone (PQQ) producing Escherichia coli Nissle 1917 (EcN) alleviates age associated oxidative stress and hyperlipidemia, and improves mitochondrial function in ageing rats.
Singh AK, Pandey SK, Saha G, Gattupalli NK.
Exp Gerontol. 2015 Jun;66:1-9. doi: 10.1016/j.exger.2015.04.001. Epub 2015 Apr 2.
PMID: 25843018 [PubMed - in process]
Protective Effect of Pyrroloquinoline Quinone (PQQ) in Rat Model of Intracerebral Hemorrhage.
Lu H, Shen J, Song X, Ge J, Cai R, Dai A, Jiang Z.
Cell Mol Neurobiol. 2015 Oct;35(7):921-30. doi: 10.1007/s10571-015-0187-5. Epub 2015 Mar 29.
PMID: 25820784 [PubMed - in process]
Effects of dietary pyrroloquinoline quinone disodium on growth, carcass characteristics, redox status, and mitochondria metabolism in broilers.
Wang J, Zhang HJ, Samuel KG, Long C, Wu SG, Yue HY, Sun LL, Qi GH.
Poult Sci. 2015 Feb;94(2):215-25. doi: 10.3382/ps/peu050. Epub 2015 Jan 20.
PMID: 25609689 [PubMed - in process]
Pyrroloquinoline quinone protects nucleus pulposus cells from hydrogen peroxide-induced apoptosis by inhibiting the mitochondria-mediated pathway.
Yang L, Rong Z, Zeng M, Cao Y, Gong X, Lin L, Chen Y, Cao W, Zhu L, Dong W.
Eur Spine J. 2015 Aug;24(8):1702-10. doi: 10.1007/s00586-014-3630-2. Epub 2014 Oct 28.
PMID: 25349108 [PubMed - in process]
Pyrroloquinoline quinone protects mouse brain endothelial cells from high glucose-induced damage in vitro.
Wang Z, Chen GQ, Yu GP, Liu CJ.
Acta Pharmacol Sin. 2014 Nov;35(11):1402-10. doi: 10.1038/aps.2014.4. Epub 2014 Oct 6.
PMID: 25283505 [PubMed - indexed for MEDLINE] Free PMC Article
Involvement of ERK1/2 pathway in neuroprotective effects of pyrroloquinoline quinine against rotenone-induced SH-SY5Y cell injury.
Zhang Q, Zhang J, Jiang C, Qin J, Ke K, Ding F.
Neuroscience. 2014 Jun 13;270:183-91. doi: 10.1016/j.neuroscience.2014.04.022. Epub 2014 Apr 19.
PMID: 24755484 [PubMed - indexed for MEDLINE]
Dietary pyrroloquinoline quinone (PQQ) alters indicators of inflammation and mitochondrial-related metabolism in human subjects.
Harris CB, Chowanadisai W, Mishchuk DO, Satre MA, Slupsky CM, Rucker RB.
J Nutr Biochem. 2013 Dec;24(12):2076-84. doi: 10.1016/j.jnutbio.2013.07.008.
PMID: 24231099 [PubMed - indexed for MEDLINE] Free Article
Altering pyrroloquinoline quinone nutritional status modulates mitochondrial, lipid, and energy metabolism in rats.
Bauerly K, Harris C, Chowanadisai W, Graham J, Havel PJ, Tchaparian E, Satre M, Karliner JS, Rucker RB.
PLoS One. 2011;6(7):e21779. doi: 10.1371/journal.pone.0021779. Epub 2011 Jul 21.
PMID: 21814553 [PubMed - indexed for MEDLINE] Free PMC Article
Pyrroloquinoline quinone stimulates mitochondrial biogenesis through cAMP response element-binding protein phosphorylation and increased PGC-1alpha expression.
Chowanadisai W, Bauerly KA, Tchaparian E, Wong A, Cortopassi GA, Rucker RB.
J Biol Chem. 2010 Jan 1;285(1):142-52. doi: 10.1074/jbc.M109.030130. Epub 2009 Oct 27.
PMID: 19861415 [PubMed - indexed for MEDLINE] Free PMC Article
Pyrroloquinoline quinone preserves mitochondrial function and prevents oxidative injury in adult rat cardiac myocytes.
Tao R, Karliner JS, Simonis U, Zheng J, Zhang J, Honbo N, Alano CC.
Biochem Biophys Res Commun. 2007 Nov 16;363(2):257-62. Epub 2007 Aug 14.
PMID: 17880922 [PubMed - indexed for MEDLINE] Free PMC Article
Pyrroloquinoline quinone nutritional status alters lysine metabolism and modulates mitochondrial DNA content in the mouse and rat.
Bauerly KA, Storms DH, Harris CB, Hajizadeh S, Sun MY, Cheung CP, Satre MA, Fascetti AJ, Tchaparian E, Rucker RB.
Biochim Biophys Acta. 2006 Nov;1760(11):1741-8. Epub 2006 Jul 25.
PMID: 17029795 [PubMed - indexed for MEDLINE]
Comparison of pyrroloquinoline quinone and/or metoprolol on myocardial infarct size and mitochondrial damage in a rat model of ischemia/reperfusion injury.
Zhu BQ, Simonis U, Cecchini G, Zhou HZ, Li L, Teerlink JR, Karliner JS.
J Cardiovasc Pharmacol Ther. 2006 Jun;11(2):119-28.
PMID: 16891289 [PubMed - indexed for MEDLINE]
Pyrroloquinoline quinone modulates mitochondrial quantity and function in mice.
Stites T, Storms D, Bauerly K, Mah J, Harris C, Fascetti A, Rogers Q, Tchaparian E, Satre M, Rucker RB.
J Nutr. 2006 Feb;136(2):390-6.
PMID: 16424117 [PubMed - indexed for MEDLINE] Free Article
Antioxidant and pro-oxidant properties of pyrroloquinoline quinone (PQQ): implications for its function in biological systems.
He K, Nukada H, Urakami T, Murphy MP.
Biochem Pharmacol. 2003 Jan 1;65(1):67-74.
PMID: 12473380 [PubMed - indexed for MEDLINE]